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Gallstones are these tough little stones that form inside your gallbladder, which sits just under your liver on the right side of your belly. The gallbladder’s a small, pear-shaped organ that stores bile—a digestive juice your body sends into your small intestine to help break down food. Here’s how it works: after you eat, your gallbladder squeezes out bile, and that helps with digestion.
Now, gallstones are basically hard clumps of bile. They actually form in the liver but end up being stored in the gallbladder. Their size? All over the place. Some are tiny, like a seed, while others can get as big as a golf ball. You might have just one or a whole bunch at once.
Sometimes, these stones move and block the bile duct. That’s when things get tricky. At first, gallstones usually don’t cause any symptoms, so you might not even know you have them. No treatment needed at that point. But if they start causing trouble—like pain, nausea, or vomiting—it gets a lot harder to ignore. The pain can hit for a few minutes or drag on for hours. When symptoms get severe, doctors often recommend surgery to remove the gallbladder.
If you ignore gallstones for too long, you risk running into serious complications that are much harder to deal with. So, it’s important to stay on top of things and get the right treatment when you need it.
What Are Gallstones?
Gallstones, also known as cholelithiasis, are hardened and compacted deposits formed from bile that collect in the gallbladder and bile ducts. Gall (bile) stones are simply stones made of bile. When your gallbladder, containing bile, is full, it will store excess bile that was produced by your liver, which is delivered through the bile ducts to various parts of your biliary tract.
In the medical field, the term cholelithiasis is used to denote the general condition of having gallstones. Chole means "bile," while lithiasis means "the formation of stones." Gallstones are formed when solid materials, known as bile crystal or crystals, become trapped in the gallbladder when the sediment from bile becomes too thick to move out of the gallbladder and into the bile duct and liver.
Gallbladder stones are classified as cholesterol or pigment stones.
Cholesterol Gallstones
Cholesterol gallstones are the most frequently formed type of gallstones (approximately 80% of cases) and are primarily composed of hardened cholesterol. The stones appear yellow or greenish and develop as a result of high concentrations of cholesterol within the bile. High levels of cholesterol are formed when the liver releases too much cholesterol or when the gallbladder is unable to empty normally.
Pigment Gallstones
In an individual with specific health conditions that impact the breakdown of red blood cells, pigment gallstones are formed from excess bilirubin. This type of gallstone forms when an individual has a high level of bilirubin in the bile. The following are certain diseases/conditions that could potentially lead to an increase in the level of bilirubin in the bile, thereby increasing the risk of developing pigment gallstones; these diseases/conditions are hemolytic anemia, liver cirrhosis, and conditions impacting the biliary tract.
Pigment stones are smaller than other stone types and darker in colour. The presence of excess bilirubin is how these stones form. Disease states, such as cirrhosis and disorders affecting the blood, are two conditions that would increase the likelihood of the formation of these stones.
Watchful waiting
If gallstones are small and aren’t causing problems, doctors usually just keep an eye on things. No treatment right away — just watching for any symptoms that show up.
Medication
There are some drugs that can dissolve gallstones, but it’s a slow process. Plus, they don’t work for every type of stone, and sometimes you still need other treatments.
Laparoscopic Cholecystectomy
This is the go-to treatment when gallstones start causing symptoms. Surgeons remove the gallbladder using small incisions and a laparoscope, so recovery’s quicker than with open surgery. And honestly, you don’t need your gallbladder for digestion, so most people don’t notice much difference once it’s gone.
Endoscopic Retrograde Cholangiopancreatography (ERCP)
Doctors use ERCP to get rid of stones that have slipped into the bile ducts. They guide a thin tube with a camera down your throat and into your small intestine, then fish out the stones right there.
Extracorporeal Shock Wave Lithotripsy (ESWL)
This one’s non-invasive. Shock waves break the stones into smaller pieces so they can pass naturally through your digestive system.
Percutaneous Cholecystostomy
If someone can’t have surgery, maybe because of other health issues, doctors can drain the gallbladder by putting a tube through the skin. It relieves pain and helps with symptoms, especially when things get severe.
Gallstone removal treatments in India can cost anywhere from $500 to $1500, depending on the hospital's facilities, the surgeon's ability, the patient's condition, and any problems from their symptoms.
Gallstones may produce varying symptoms, with some people remaining asymptomatic. Some of the common symptoms people with gallstones may experience are as follows:
Pain: Either a sharp and sudden pain or a dull ache located in the upper right side of the abdomen or upper back.
Nausea/vomiting: People may experience nausea/vomiting in conjunction with abdominal pain.
Indigestion/Bloating: Many people with gallstones may experience symptoms of either indigestion/bloating following meals as a result of gallstones.
Fatigue: As a result of the pain/discomfort associated with gallstones, many people will feel fatigued/weak.
Jaundice: Jaundice may occur if a blockage of the common bile duct (CBD) occurs from gallstones, causing yellowing of the eyes and skin.
Clay-Colour Stools: Gallstones that have become complicated often cause the stool to appear pale/clay in colour.
Fever/chills: Fever/chills may occur as a result of inflammation/infection of the gallbladder or bile.
Loss of Appetite: Gallstones may decrease a person's appetite because of pain/discomfort.
Sweating: Sweating may occur in conjunction with abdominal pain in certain people who suffer from gallstones.
Rapid Heart Rate: A rapid heart rate may result from the pain/discomfort caused by gallstones.
There are numerous factors that can lead to the development of gallstones, so one has to be familiar with the risk factors and the possible causes. The following are some of the common contributors:
Obesity and fast weight loss: Overweight or fast weight loss can be a factor that contributes to the development of gallstones.
Genetics: A positive family history of gallstones may predispose an individual to the development of the same.
Increased bilirubin concentrations in the blood: Underlying causes of high bilirubin (e.g. haemolysis) elevate the risk of the formation of pigment stones.
Hormonal abnormalities: Hormonal variations during pregnancy or due to some medications such as birth control pills or oestrogen replacement therapy could lead to the risk of developing gallstones.
Inflammatory bowel disease: Crohn's disease and ulcerative colitis are inflammatory bowel diseases that may put a person at risk of developing gallstones.
Metabolic disorders: Gallbladder stones can be caused by conditions such as diabetes, which is a metabolic disorder.
Long-term fasting, or high fat, cholesterol diet: Some of the dietary conditions may predispose to the development of gallstones.
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